Dr. Shen began to do research work at Dr. David Hajjar’s lab, Department of Pathology, WCM, in 2001. He joined Dr. Melnick’s lab in 2011. Dr. Shen has more than 20-year experience of management of mouse colonies. Now he manages the Melnick lab’s expanding geneticially modified animal colonies and oversees one of the largest animal programs at WCM (~2000 cages). He supervises technicians and together they manage all the routine and complex breeding of these colonies, including genotyping and mouse characterization, breeding, drug testing, and xenografting of leukemia, lymphoma, and solid tumor cells. He works with the faculty and post-docs in establishing cohort needs and addressing any issues that arise. He also involves conduct and design of experiments to determine the role of oncogenes and/or tumor suppressor genes in hematological and solid malignancies, including bone marrow transplantation experiments.
Dr. Shen has many publications in peer-reviewed journals, including first-authored publications in the Journal of Lymphoma, the Journal of Clinical Pediatrics, and the Canadian Journal of Physiology and Pharmacology